Seahawks vs 49ers Odds - Hasselbeck, Seahawks will edge 49ers in West showdown
The Seahawks vs 49ers odds will pit what appears to be the top two teams in the NFC West. After the 49ers won in Arizona and the Seahawks rocked the Rams in Week 1 online betting, these two teams appear to be the cream of the crop. But the Seahawks are clearly the better team, especially at the quarterback position.
Seahawks vs 49ers odds: 49ers -1
- WHAT: NFL betting
- WHEN: Sunday, September 20th – 4:15 PM ET
- WHERE: Candlestick Park – San Francisco, CA
- PICK: Seahawks -1, 39.5
Seahawks vs 49ers odds maker breakdown: The Storyline
The Seahawks were ravaged by injuries last year and took a year off from winning the West. This year, they appear to be back. A win in San Francisco would make an early statement to sportsbook bettors that Seattle are the team to beat in the West. Similarly, San Francisco can make the same statement with a win. They aren’t being taken seriously right now because Shaun Hill is their starting quarterback, but with a win here, they definitely will be. Betting Edge: Even
Seahawks vs 49ers odds maker breakdown: Offense
The Seahawks offense really got rolling in Week 1, but we have to assume that their running game won’t be as fluid this week against a better 49ers defense. Even so, the Seahawks offensive line was a big concern heading into the season and it held up well in the opener. If Matt Hasselbeck has time, he’s going to pick apart the 49ers defense. The 49ers offense, on the other hand, is a work in progress. Even calling it that might be an overstatement. Hill is very limited as a quarterback and he really doesn’t have any No. 1 targets to work with. If the Seahawks shut down Frank Gore, the 49ers offense will have a tough time scoring points. Betting Edge: Seahawks
Seahawks vs 49ers odds maker breakdown: Defense
While most people will be quick to give this edge to the 49ers, take a good look at this Seahawks defense - they could be one of the best in the league. The Seahawks shut out the Rams in Week 1, notching three sacks and limiting Steven Jackson to 76 yards on 16 carries. That’s notable. The 49ers defense is also a competent unit and while they don’t have the talent the Seahawks do, they get the job done with moxie and coaching. They did a good job against the Cardinals last week but the Cardinals did shoot themselves in the foot a few times. Still, this is a stout defense when they play at home. Betting Edge: Even
Seahawks vs 49ers odds maker breakdown: Notable Injuries
The Seahawks have a couple of injuries in their linebacking corps. LeRoy Hill suffered a groin strain and will miss this contest while Lofa Tatupu suffered a hamstring injury, but will be able to play. Betting Edge: 49ers
Seahawks vs 49ers odds for total: 39.5
With two good defenses and two running games that will likely be shut down this week, the under looks like a solid play. Seattle has an offense to carry this over but they will be on the road against a good defense. Under is the way to play this total. Pick: Under
Seahawks vs 49ers betting breakdown: Outlook and Pick
NFL betting fans should take notice: Seattle is back. While they might not be an NFC contender, they are the best team in the West and they’ll show it this week. D.J.’S PICK: Seahawks +1
Want more sports betting analysis? Visit the BetOnline.com Betting Edge daily. And for more on the Seahawks vs 49ers odds, check out our stats center. D.J. Tomkins is one of BetOnline.com's NFL experts.


